Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
BASIC RADIOBIOLOGY RTP150 2. Semester 2 + 0 2.0 3.0

Prerequisites None

Language of Instruction Turkish
Course Level Associate's Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Özge Nur KANAT
Assistants
Goals The aim of this course is to inform students about the types of radiation and to explain the effects of radiation on living cells, tissues, systems and metabolisms, and to raise awareness about the use of radiation and protection from radiation.
Course Content Basic and Molecular Cell Biology; Cell Cycle/Checkpoints and Radiation sensitivities of different phases in the cell cycle, Dividing cells and the concept of survival; Introduction to Radiobiology, Definition and Types of Radiation; Irradiation-induced damage and DNA damage response; Cell death after irradiation: how, when and why do cells die?; Radiation dose-response relationships; Linear energy transfer (LET) and relative biological efficiency (RBE); Types of cellular damage caused by radiation, Factors affecting the cell survival curve; Effect of radiation on tissues and organs; Tumor kinetics, Model tumor systems, Tumor response to radiation; Late effects of radiation, Genetic effects, Carcinogenic effects, Effects of radiation on embryo and fetus; Radiation protection
Learning Outcomes 1) Student distinguishes types of radiation
2) Student explains the effects of radiation on cell, tissue, system and metabolism.
3) Öğrenci radyasyonun normal ve tümör dokularındaki etkilerini bilir
4) The student learns the agents that increase or decrease the effects of radiation in living systems
5) The student learns the ways of protection from radiation.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Basic and Molecular Cell Biology Lecture; Question Answer; Problem Solving; Discussion; Case Study
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
2. Week Cell Cycle/Checkpoints and Radiation sensitivities of different phases in the cell cycle, Dividing cells and the concept of survival Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
3. Week Introduction to Radiobiology, Definition and Types of Radiation Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
4. Week Irradiation-induced damage and DNA damage response Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
5. Week Cell death after irradiation: how, when and why do cells die? Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
6. Week Radiation dose-response relationships Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
7. Week Linear energy transfer (LET) and relative biological efficiency (RBE) Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
8. Week Midterm Question Answer
Brainstorming; Opinion Pool; Speech Loop; Workshop
Problem Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
9. Week Types of cellular damage caused by radiation, Factors affecting the cell survival curve Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
10. Week Effect of radiation on tissues and organs I Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
11. Week Effect of radiation on tissues and organs II Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Buzz Group; Large Group Discussion
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
12. Week Tumor kinetics, Model tumor systems, Tumor response to radiation Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
13. Week Late effects of radiation, Genetic effects, Carcinogenic effects, Effects of radiation on embryo and fetus Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
14. Week Radiation protection Lecture; Question Answer; Problem Solving; Discussion; Case Study; Role Play
Brainstorming; Opinion Pool; Speech Loop; Colloquium; Large Group Discussion; Workshop
Problem Based Learning; Storyline; Scenario Based Learning; Brain Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)

Sources Used in This Course
Recommended Sources
Temel Radyobiyoloji, Atilla Özalpan, 2001, Haliç Üniversitesi Yayınları, İstanbul.

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3DK4DK5
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PY5555555
PY6555555
PY7555555
PY8455500
PY9555555
PY10444445
PY11555555
PY12555555
PY13555555
PY14333333
PY16333333
PY17222222

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
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ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 3
Homework 2 1
Activity (Web Search, Library Work, Trip, Observation, Interview etc.) 5 2
Midterm Exam 1 1
Time to prepare for Midterm Exam 1 5
Final Exam 1 1
Time to prepare for Final Exam 1 8
1 1
1 1
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload