Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
Biochemical Toxiology 55431021 2 + 0 2.0 6.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery Face-to-face teaching, interactive discussion, seminar
Course Coordinator
Instructors
Assistants
Goals Understanding the historical development of biochemical toxicology, understanding of its principles and techniques, cellular interaction of toxic chemicals, enzyme proteins, genes and polymorphisms that catalyze biotransformation of xenobiotics, biochemical mechanisms of some organic chemicals and toxic effects on human health
Course Content The scope of biochemical toxicology, mechanism of effect of toxic chemicals, pathway of toxic substances in the organism, toxicokinetic, toxicodynamic, biochemical toxicological evaluation of some substances
Learning Outcomes 1) Knowledge of the principles and mechanisms of biochemical toxicology
2) Knowledge about biochemical mechanisms of some organic chemicals and toxic effects on human health
3) Knowledge about the historical development of biochemical toxicology,

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Introduction to biochemical toxicology Lecture; Question Answer; Discussion; Case Study
Brainstorming; Opinion Pool; Colloquium
Project Based Learning; Case Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
2. Week Definition and scope Biochemical toxicology Lecture; Question Answer; Discussion
Brainstorming; Colloquium
Project Based Learning 		Presentation (Including Preparation Time)
3. Week Absorption and distribution of toxicants. Lecture; Question Answer; Discussion
Brainstorming; Colloquium
Problem Based Learning 		Homework Presentation (Including Preparation Time)
4. Week Chemical transporters Lecture; Question Answer; Discussion
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
5. Week Metabolism of Chemicals Lecture; Question Answer
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
6. Week Factors affecting metabolism of toxicants Lecture; Question Answer
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
7. Week Elimination of toxicants Lecture; Question Answer
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
8. Week Midterm examination Lecture; Discussion
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
9. Week Toxicokinetics. Lecture; Question Answer
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
10. Week Toxicodynamics Lecture; Question Answer
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
11. Week Enzyme inhbition Lecture; Question Answer
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
12. Week Enzyme induction Lecture; Question Answer
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
13. Week Biochemical toxicologic examination of acetaminophen Lecture; Question Answer
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
14. Week Biochemical toxicologic examination of haloalkanes Lecture; Question Answer
Brainstorming; Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.
1. Principles of Biochemical Toxicology, John Timbrell, CRC Press; 4. edition, 2008. 2. Casarett & Doull's Essentials of Toxicology, Curtis D. Klaassen,‎ John B. Watkins III (Yazarlar) McGraw-Hill Education / Medical; 3 edition, August 17, 2015.

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25000
PY35000
PY45000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 2
Homework 14 2
Presentation (Including Preparation Time) 12 2
Midterm Exam 1 2
Time to prepare for Midterm Exam 10 2
Final Exam 1 2
Time to prepare for Final Exam 14 2
1 2
1 2
1 2
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
Quick Access Hızlı Erişim Genişlet
Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload