Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
SEPARATION TECHNIQUES 33703019 4 + 0 4.0 11.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Sibel Ayşıl ÖZKAN
Assistants
Goals The aim of this course is to provide theoretical knowledge on seperation methods used for drug analysis in pharmaceutical sciences
Course Content The corse content includes history of separation methods, an introduction to separation methods, theoretical basis of separation methods, extraction techniques and applications, distillation, sublimation, electrophoresis, romatographic techniques, paper chromatography, column chromatography, thin layer chromatography, bioaffinity chromatography, ion-changing chromatography, molecular sieving chromatography, gas chromatography, high performance liquid chromatography
Learning Outcomes 1) The student develops analytical methods for the simultaneous determination of drug active compounds
2) The student would have the knowledge of the use of equipments and method implementation.
3) Student presents the results as a report, interprets and uses the data.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week History of separation methods Lecture
Colloquium
Project Based Learning
Homework
2. Week An introduction to separation methods Lecture
Colloquium
Project Based Learning
Homework
3. Week Theoretical basis of separation methods Lecture
Colloquium
Project Based Learning
Homework
4. Week Extraction techniques and applications Lecture
Colloquium
Project Based Learning
Homework
5. Week Distillation, sublimation, electrophoresis Lecture
Colloquium
Project Based Learning
Homework
6. Week Chromatographic techniques Lecture
Colloquium
Project Based Learning
Homework
7. Week Paper chromatography Lecture
Colloquium
Project Based Learning
Homework
8. Week Column chromatography Lecture
Colloquium
Project Based Learning
Homework
9. Week Thin layer chromatography Lecture
Colloquium
Project Based Learning
Homework
10. Week Bioaffinity chromatography Lecture
Colloquium
Project Based Learning
Homework
11. Week Ion changing chromatography Lecture
Colloquium
Project Based Learning
Homework
12. Week Molecular sieving chromatography Lecture
Colloquium
Project Based Learning
Homework
13. Week Gas chromatography Lecture
Colloquium
Project Based Learning
Homework
14. Week High performance liquid chromatography Lecture
Colloquium
Project Based Learning
Homework

Sources Used in This Course
Recommended Sources
Cazes, J., Scott, R.P.W., Chromatography Theory, Marcel Dekker, 2002
Lunn, G, HPLC Methods for Pharmaceutical Analysis, John Wiley and Sons Inc, 2000
Skoog, D.A., Holler, F.J., Nieman, T.A., Çeviri Editörleri E. Kılıç, F. Köseoğlu, H.Yılmaz, Principles of Instrumental Analysis, Bilim Yayıncılık, 1992
Snyder, L.R., Kirkland, J.J., Glajch, J.L. , Practical HPLC Method Development, 2nd Ed., John Wiley and Sons Inc., New York, 1997
Yıldız, A., Genç, Ö.. Instrumental Analysis, Hacettepe University Publications, 1993

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25000
PY35000
PY45000
PY55000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 4
Work Hour outside Classroom (Preparation, strengthening) 14 10
Homework 7 8
Presentation (Including Preparation Time) 2 30
Midterm Exam 1 1
Time to prepare for Midterm Exam 1 10
Final Exam 1 1
Time to prepare for Final Exam 1 10
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information