Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
CONCEPTS IN REGENERATIVE MEDICINE 56903001 3 + 0 3.0 6.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery 100% theoretical
Course Coordinator
Instructors
Assistants
Goals To introduce the basic concepts and application approaches of regenerative medicine, to develop the ability to think about regenerative medicine.
Course Content Basic Concepts. Regenerative Medicine Industry. In-vitro Tissue Development. Culture Types. Tissue Engineering. Bioreactors. Body Reaction to Biografts. In vivo Tracking of Grafts. Angiogenesis and Vasculogenesis. Clinical Applications and Developments
Learning Outcomes 1) Get information about regenerative medicine concepts, development and application areas
2) To have an understanding about regenerative medicine applications ve current developments
3) Get information about the potential use on clinical applications

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Introduction, Definitions and Basic Concepts, Cell Sources, Developmental History and Current Approaches, the Concept of Translational Research, Regenerative Medicine Industry and Market. Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
2. Week In vitro Tissue Development, Developmental Mechanisms, Differentiation, Backward Differentiation, Cell – Extracellular Matrix Interactions, Cell Adhesion, Types of Cell Culture. Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
3. Week Definition of Tissue Engineering, Tissue Engineering Biomaterials, Structure – Property Relationships between Biological Materials, Synthetic, Hybrid and Composite Scaffolds, Biomimetic, Cell Layer Engineering, Surface Engineering Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
4. Week Definition of Tissue Engineering, Tissue Engineering Biomaterials, Structure – Property Relationships between Biological Materials, Synthetic, Hybrid and Composite Scaffolds, Biomimetic, Cell Layer Engineering, Surface Engineering Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
5. Week Bioreactors, Mechanical Determinants of Tissue Development, Mechano-Stimulated Systems, Remodeling, Bioartificial Organs, Support Systems, Controlled Release Systems. Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
6. Week Bioreactors, Mechanical Determinants of Tissue Development, Mechano-Stimulated Systems, Remodeling, Bioartificial Organs, Support Systems, Controlled Release Systems. Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
7. Week Body Response to the Biografts and Cellular Adaptation. Immune Response, Necrosis and Apoptosis, Biocompatibility and Biodegradability, In vitro and In vivo Tests. In vivo Tracking of the Grafts. Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
8. Week Angiogenesis and Vasculogenesis, Angiogenic Factors, Receptors in Angiogenesis, Endothelial Cells, Ischemic Tissues, Preparation of the Transplant location for the Vascular Recipients. Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
9. Week Applications and Developments: Orthopedic / Maxillofacial / Dental Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
10. Week Applications and Developments: Cardiovascular Tissues Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
11. Week Applications and Developments: Neural Tissues Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
12. Week Applications and Developments: Epithelial Tissues Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
13. Week Discussion - general evaluation Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)
14. Week Discussion - general evaluation Lecture; Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Süreli Yayınlar: • Regenerative Medicine • Tissue Engineering A, B, C • Journal of Tissue Engineering & Regenerative Medicine • Journal of Cellular and Molecular Medicine • Stem Cells Translational Medicine Kitaplar: • Principles in Tissue Engineering, 2nd ed.; eds. Lanza, Langer, Vacanti, Academic Press, 2000. • Tissue Engineering, Stem Cells and Gene Therapies; ed. Elçin, Kluwer-Plenum Press, 2003. • Kök Hücre Biyolojisi ve Klinik Uygulamalar, TÜBA Raporları, Ankara, 2009.

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25000
PY35000
PY45000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 16 4
Work Hour outside Classroom (Preparation, strengthening) 6 6
Homework 4 4
Presentation (Including Preparation Time) 4 4
Project (Including Preparation and presentation Time) 2 2
Report (Including Preparation and presentation Time) 2 2
Activity (Web Search, Library Work, Trip, Observation, Interview etc.) 2 2
Practice (Teaching Practice, Music/Musical Instrument Practice , Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice) 2 2
Seminar 2 2
Internship 2 2
Quiz 2 2
Time to prepare for Quiz 1 1
Time to prepare for Midterm Exam 1 1
Final Exam 2 2
Time to prepare for Final Exam 1 1
1 1
1 1
1 1
2 2
1 1
2 2
Dönem Sonu Sınavı (DSS) 1 1
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
Quick Access Hızlı Erişim Genişlet
Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload