Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
INTRODUCTION TO QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIPS IN DRUG DESIGN 34101013 0 + 0 2.0 2.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Ayşe Selen ALP
Assistants
Goals Understanding of the rational and analytical methods, used in the design and development of new pharmaceutical active substances, are discussed.
Course Content Comprehension of the rational content of quantitative structure-activity relationships on drug design and development
Learning Outcomes 1) The design of new pharmaceutical active substance has the knowledge of quantitative structure-activity relationships and computer practices.
2) It has information about the statistical evaluation of quantitative and biological analysis results of pharmaceutical active substances.
3) It is continued personal and professional development by using lifelong learning skills in the field of Pharmaceutical Chemistry.
4) It follows developments in information and technology in order to increase the effectiveness of R&D studies, and it achieves accurate and current information sources.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Design studies of pharmaceutical active compounds Lecture; Question Answer; Problem Solving
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
2. Week Rational approaches and importance Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
3. Week Mechanistic Design Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
4. Week Structure-Activity Relationships Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
5. Week Historical Development of Structure-Activity Relationships Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
6. Week Physicochemical parametrization Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
7. Week Quantitative Structure-Activity Relationships Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
8. Week Importance of Quantitative Structure-Activity Relationships Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
9. Week Historical Development of Quantitative Structure-Activity Relationships Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
10. Week Methods of Quantitative Structure-Activity Relationships Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
11. Week Hansch analysis method Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
12. Week Linear Quantitative Structure-Activity Relationships Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
13. Week Non-Linear Quantitative Structure-Activity Relationships Lecture; Question Answer; Problem Solving; Discussion
Opinion Pool
Problem Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
14. Week Homework presentation Lecture; Question Answer; Problem Solving; Discussion
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Akı-Şener, E., Yalçın, İ. (2003) Farmasötik / Medisinal kimya'da İlaç Etken Madde Tasarım Yöntemleri 1, Kantitatif Yapı-Etki İlişkileri Analizleri (QSAR), Ankara Üniversitesi Basımevi., Ankara.
Türkoğlu, A. (1998). Karşılaştırmalı Eğitim. Adana: Baki Kitabevi

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3DK4
PY150000
PY250000
PY350000
PY450000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 1
Presentation (Including Preparation Time) 8 1
Activity (Web Search, Library Work, Trip, Observation, Interview etc.) 14 1
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload