Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
SELECTIVE TOXICITY 34304015 2 + 0 2.0 6.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors İlker ATEŞ
Assistants
Goals Giving information about the principals of selective toxicity and state the important role in drug development
Course Content The topics are designed to give information about the principals of selective toxicity and state the important role in drug development
Learning Outcomes 1) He/She defines the mechanisms of selective toxicity
2) He/She describes the differences in biotransformation mechanism
3) He/She explains the importance of selectivity to drug development

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Introduction to selective toxicity Lecture; Question Answer
Brainstorming
Brain Based Learning 		Presentation (Including Preparation Time)
2. Week The mechanism of selective toxicity Lecture; Question Answer
Brainstorming
Brain Based Learning 		Presentation (Including Preparation Time)
3. Week Chemical principles of selectivity Lecture; Question Answer
Brainstorming
Brain Based Learning 		Presentation (Including Preparation Time)
4. Week variation of cell Lecture; Question Answer

Brain Based Learning 		Presentation (Including Preparation Time)
5. Week variation of dissosiation mechanism Lecture; Question Answer

Brain Based Learning 		Presentation (Including Preparation Time)
6. Week Variation of biotransformation mechanism Lecture; Question Answer

Brain Based Learning 		Presentation (Including Preparation Time)
7. Week enzyme and receptor systems in selective toxicity Lecture; Question Answer

Brain Based Learning 		Presentation (Including Preparation Time)
8. Week Midterm

9. Week Covalent bond in selective toxicity Lecture; Question Answer

Brain Based Learning 		Presentation (Including Preparation Time)
10. Week Metabolite and metobolite analogs in selective toxicity Lecture; Question Answer

Brain Based Learning 		Presentation (Including Preparation Time)
11. Week Selectivity in biologic systems Lecture; Question Answer

Brain Based Learning 		Presentation (Including Preparation Time)
12. Week Lethal synthesis Lecture; Question Answer
Brainstorming
Brain Based Learning 		Presentation (Including Preparation Time)
13. Week The role of selectivity in drug development Lecture; Question Answer

Brain Based Learning 		Presentation (Including Preparation Time)
14. Week Presentation of students Question Answer; Discussion
Brainstorming
 Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Selective Toxicity, The Physico-chemical basis of therapy.
Casarett&Doull’s Toxicology: The Basic Science of Poisons.

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25000
PY35000
PY45000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 2
Homework 10 2
Presentation (Including Preparation Time) 10 2
Midterm Exam 1 2
Time to prepare for Midterm Exam 10 3
Final Exam 1 3
Time to prepare for Final Exam 14 3
1 2
1 2
1 2
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
Quick Access Hızlı Erişim Genişlet
Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload