Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY 34304067 2 + 0 2.0 6.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Aylin ÜSTÜNDAĞ
Assistants
Goals To give information about reproductive system toxicity and developmental toxicology and their mechanisms
Course Content Reproductive toxicity and developmental toxicology principles, mechanisms, samples of human events, data obtained from drugs and various chemicals
Learning Outcomes 1) He/She enhances his/her toxicology knowledge about toxicology basics, mechanisms and practices. He/She makes contact between toxicology and the other disciplines such as pharmacology, biochemistry, genetics, biophysics and forensic science which are collaborator sciences of toxicology.
2) He/She can solve the problems related with his/her field with research methods. He/She assesses and uses the original information and technologies in the field of toxicology. He/She performs in vivo or in vitro toxicological researches which investigate the detrimental effects of various factors to the organism.
3) She/He publishes scientific article in national and/or international peer-review about her/his field thereby she/he increases her/his knowledge.
4) She/He may study in toxicology field as a member of team. She/He follows up and comments about changes of legal regulations about the field and profession. "She/He follows professional and technological developments in toxicology and the related fields.
5) He/She creates functional interactions with relevant individuals and organizations by using strategic decision-making processes about the solutions of the problems related to the field of his/her

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Principles of developmental toxicology Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
2. Week The structure of reproductive system Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
3. Week General information about reproductive toxicology Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
4. Week Dose-response relationship in developmental toxicology Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
5. Week Pharmacokinetics in pregnancy Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
6. Week Transfer of drugs and xenobiotics through milk Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
7. Week Phisiological pharmacokinetic models (PBPK) Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
8. Week Midterm exam

9. Week Effects of drugs and xenobiotics on reproductive and developmental toxicology Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
10. Week Safety assessment Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
11. Week Toxicity test models Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
12. Week Mechanism-based models of reproductive and developmental toxicity Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
13. Week Valid guidelines for reproductive and developmental toxicity Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)
14. Week Invitro biomarkers related to reproductive and developmental toxicity Lecture; Discussion
Brainstorming
Project Based Learning
Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Developmental Toxicology
Essentials of Toxicology
Reproductive and Developmental Toxicology

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3DK4DK5
PY1500000
PY2500000
PY3500000
PY4500000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 2
Homework 12 2
Presentation (Including Preparation Time) 17 2
Practice (Teaching Practice, Music/Musical Instrument Practice , Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice) 2 2
Midterm Exam 1 1
Time to prepare for Midterm Exam 12 2
Final Exam 1 1
Time to prepare for Final Exam 12 2
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information