Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
SELECTIVITY IN TOXICITY 34336015 2 + 0 2.0 6.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors İlker ATEŞ
Assistants
Goals Giving information about the principals of selective toxicity and state the important role in drug development
Course Content The topics are designed to give information about the principals of selective toxicity and state the important role in drug development
Learning Outcomes 1) He/She can solve the problems related with his/her field with research methods. He/She assesses and uses the original information and technologies in the field of toxicology. He/She performs in vivo or in vitro toxicological researches which investigate the detrimental effects of various factors to the organism.
2) She/He publishes scientific article in national and/or international peer-review about her/his field thereby she/he increases her/his knowledge.
3) "She/He follows professional and technological developments in toxicology and the related fields. She/He may develop ideas and methods about her/his field using high level processes such as creative and critical thinking, problem solving and decision making."He/She examines social relations and the norms guiding these relations with a critical perspective. He/She manages the activities to develop these actions and change if necessary. "

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Introduction to selective toxicity Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
2. Week Mechanisms of selective toxicity Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
3. Week Mechanisms of selective toxicity Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
4. Week Chemical principles of selectivity Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
5. Week Differences in cell structure Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
6. Week Differences in distribution mechanisms Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
7. Week Midterm exam Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
8. Week Differences in biotransformation mechanism Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
9. Week Enzyme and receptor systems in selectivity Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
10. Week Covalent bonds in selective toxicity Lecture; Discussion
Brainstorming
Brain Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
11. Week Metabolites and their analogues in selective toxicity Lecture; Discussion
Brainstorming
Brain Based Learning
Presentation (Including Preparation Time)
12. Week Selectivity in biological systems Lecture; Discussion
Brainstorming
Brain Based Learning
Presentation (Including Preparation Time)
13. Week Lethal synthesis Lecture; Discussion
Brainstorming
Brain Based Learning
Presentation (Including Preparation Time)
14. Week The importance of selectivity in drug development Lecture; Discussion
Brainstorming
Brain Based Learning
Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Casarett&Doull’s Toxicology: The Basic Science of Poisons.
Selective Toxicity, The Physico-chemical basis of therapy.

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25000
PY35000
PY45000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 2
Homework 12 2
Presentation (Including Preparation Time) 14 2
Practice (Teaching Practice, Music/Musical Instrument Practice , Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice) 2 2
Midterm Exam 1 2
Time to prepare for Midterm Exam 8 3
Final Exam 1 2
Time to prepare for Final Exam 14 2
2 2
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information