Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
GENOTOXICITY TESTS PRACTICAL 34336044 0 + 2 1.0 2.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Aylin ÜSTÜNDAĞ
Assistants
Goals Application of test methods for the detection of genotoxic chemical substances
Course Content Genetic risk prediction, sister chromatid exchange test, micronucleus test, comet assay applications
Learning Outcomes 1) He/She enhances his/her toxicology knowledge about toxicology basics, mechanisms and practices, He/She makes contact between toxicology and the other disciplines such as pharmacology, biochemistry, genetics, biophysics and forensic science which are collaborator sciences of toxicology
2) He/She can solve the problems related with his/her field with research methods, He/She asseses and uses the original informations and technologies in the field of toxicology, He/She performes in vivo or in vitro toxicological researches which investigate the detrimental effects of various factors to the organism
3) She/He may study in toksicology field as a member of team, She/He follows up and comments about changes of legal regulations about the field and profession, She/He follows professional and technological developments in toxicology and the related fields

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Genotoxicity definition Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
2. Week Genotoxicity tests Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Scenario Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
3. Week Single cell gel electrophoresis (COMET Assay) test method applications Lecture; Question Answer; Problem Solving
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Scenario Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
4. Week Single cell gel electrophoresis (COMET Assay) test method applications Lecture; Question Answer; Problem Solving
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Scenario Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
5. Week Sister chromatid exchange test applications Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Brain Based Learning 		Homework Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
6. Week Sister chromatid exchange test applications Lecture; Question Answer; Problem Solving
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Brain Based Learning 		Homework Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
7. Week Chromosomal damage test applications Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Brain Based Learning 		Homework Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time)
8. Week Chromosomal damage test applications Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Scenario Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
9. Week Midterm exam Lecture; Question Answer; Problem Solving
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Brain Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
10. Week Micronucleus test applications Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Brain Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
11. Week Micronucleus test applications Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Scenario Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
12. Week ARA-C CBMN test applications Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Scenario Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
13. Week ARA-C CBMN test applications Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Scenario Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
14. Week Evaluation of genotoxicity test results Lecture; Question Answer; Discussion
Brainstorming; Opinion Pool; Speech Loop
Problem Based Learning; Storyline; Brain Based Learning 		Homework Presentation (Including Preparation Time) Activity (Web Search, Library Work, Trip, Observation, Interview etc.)

Sources Used in This Course
Recommended Sources
In Vitro Methods in Pharmaceutical Research
Principles of Genetic Toxicology

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25000
PY35000
PY45000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 1
Work Hour outside Classroom (Preparation, strengthening) 14 1
Practice (Teaching Practice, Music/Musical Instrument Practice , Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice) 10 1
Midterm Exam 1 1
Time to prepare for Midterm Exam 7 1
Final Exam 1 1
Time to prepare for Final Exam 14 1
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
Quick Access Hızlı Erişim Genişlet
Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload