Course Information

Course Title	Code	Semester	L+U Hour	Credits	ECTS
TUMOR IMMUNOLOGY-1	23563009		3 + 0	3.0	8.0

Prerequisites

None

Language of Instruction	Turkish
Course Level	Graduate Degree
Course Type	Compulsory
Mode of delivery
Course Coordinator
Instructors	Hakan AKBULUT
Assistants	Fatma Gizem SONUGÜR Cansu BABAHAN
Goals	To gain perspective about develeopment of the basis of cancer immunothreapy, immunotheraphy and other treatment strategies combinations.
Course Content	The role of immune system in cancer development and the immune responses against cancer and disease caused by this mechanism will be lectured. Biologic concepts of tumor immunology, cell and immunologic responses against neoplasms, metastasis immunology,tumor antigens, immune treatment in cancer,adoptive immunotherapy, gen therapy, cellular treatment,targeted therapy transplantation immunobiology will be lectured.
Learning Outcomes	1) At the end of this course, current knowledge about cancer immunology will be gained. 2) At the end of this course, the students will gain a perspective on the basis of cancer immunotherapy and the development of combination strategies of immunotherapy and other treatment modalities in cancer. 3) The students will learn to do project and present by asking current original questions about tumor immunology.

Weekly Topics (Content)

Week	Topics	Teaching and Learning Methods and Techniques	Study Materials
1. Week	Tumor antigens	Lecture; Question Answer; Discussion	Presentation (Including Preparation Time)
2. Week	İmmunological surveillance and immune editing of cancer	Lecture; Question Answer; Problem Solving; Discussion Brainstorming	Presentation (Including Preparation Time)
3. Week	Dendritic cells in cancer	Lecture; Question Answer; Problem Solving; Discussion Brainstorming	Presentation (Including Preparation Time)
4. Week	Cytotoxic T Lymphocyte in Cancer	Lecture; Question Answer; Discussion Brainstorming	Presentation (Including Preparation Time)
5. Week	Natural killer cells in cancer	Lecture; Question Answer; Discussion Brainstorming	Presentation (Including Preparation Time)
6. Week	Regulatory T cells in Cancer	Lecture; Question Answer; Discussion Brainstorming	Presentation (Including Preparation Time)
7. Week	Tumor Microenviroment and Immunity	Lecture; Question Answer; Problem Solving; Discussion Brainstorming	Presentation (Including Preparation Time)
8. Week	Chemokines in cancer	Lecture; Question Answer; Problem Solving; Discussion Brainstorming	Presentation (Including Preparation Time)
9. Week	Adhesion molecules in cancer	Lecture; Question Answer; Problem Solving; Discussion Brainstorming	Presentation (Including Preparation Time)
10. Week	Immunology of tumor metastasis	Lecture; Question Answer; Discussion Brainstorming	Presentation (Including Preparation Time)
11. Week	Apoptosis and cancer	Lecture; Question Answer; Problem Solving; Discussion Brainstorming	Presentation (Including Preparation Time)
12. Week	Natural Killer Cell Polymorphism and Cancer Treatment	Lecture; Question Answer; Problem Solving; Discussion Brainstorming	Presentation (Including Preparation Time)
13. Week	Adoptive immunotherapy	Lecture; Question Answer; Problem Solving; Discussion Brainstorming	Presentation (Including Preparation Time)
14. Week	Cancer Vaccines and Genetically Modified Cancer Vaccines	Lecture; Question Answer; Problem Solving; Discussion Brainstorming	Presentation (Including Preparation Time)

Sources Used in This Course

Recommended Sources

Abul K. Abbas, Andrew H. H. Lichtman, Shiv Pillai MBBS. Basic Immunology: Functions and Disorders of the Immune System, latest Edition

Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai. Cellular and Molecular Immunology, Latest Edition

David Male, Jonathan Brostoff, David B Roth, and Ivan M Roitt. Immunology Latest ed

David Male, Jonathan Brostoff, David B Roth, and Ivan M Roitt. Immunology Latest edt

Mark Peakman. Basic And Clinical Immunology

obert R. Rich, Thomas A. Fleisher, William T. Shearer, Harry W. Schroeder Jr., Anthony J. Frew, and Cornelia M. Weyand. Clinical Immunology: Principles and Practice, Latest edition

Relations with Education Attainment Program Course Competencies

Program Requirements	Contribution Level	DK1	DK2	DK3
PY1	5	0	0	0
PY2	5	0	0	0
PY3	5	0	0	0
PY4	5	0	0	0

*DK = Course's Contrubution.

	0	1	2	3	4	5
Level of contribution	None	Very Low	Low	Fair	High	Very High

ECTS credits and course workload

Event	Quantity	Duration (Hour)	Total Workload (Hour)
Course Duration (Total weeks*Hours per week)	14	4	56
Work Hour outside Classroom (Preparation, strengthening)	14	8	112
Presentation (Including Preparation Time)	3	6	18
Project (Including Preparation and presentation Time)	3	4	12
Report (Including Preparation and presentation Time)	1	2	2
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)	1	8	8
Final Exam	1	3	3
Time to prepare for Final Exam	1	24	24
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course			30

Quick Access

Tumor Biology (MS)
With Thesis

Course Information

Course Information
Weekly Topics (Content)
Sources Used in This Course
Relations with Education Attainment Program Course Competencies
ECTS credits and course workload

Course Information

Course Information

Weekly Topics (Content)

Sources Used in This Course

Relations with Education Attainment Program Course Competencies

ECTS credits and course workload

Quick Access

Tumor Biology (MS) With Thesis

Course Information

Tumor Biology (MS)
With Thesis