Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
BIOISTATISTICS PHM1009 1. Semester 2 + 0 2.0 2.0

Prerequisites None

Language of Instruction English
Course Level Bachelor's Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Zahide KOCABAŞ
Assistants Rabia ALBAYRAK DELİALİOĞLU
Goals Objectives of this course are: to give Information on the basic principle of statistics; to explain necessity of description of the statistical distribution; to emphasize the necessity of hypothesis control when a reasearch is completed; to explain and give Information on the statistical methods to be used to evaluate the data collected from the experiments (research)
Course Content The basic concepts of statistics, collection of data, type of data (continuous and discrete), descriptive statistics, Measures of central tendency (arithmetic mean, median, mode, geometric mean, harmonic mean), Measures of dispersion (range, variance, standard deviation, coefficient of variation), Statistical distributions, Binomial distribution, Poisson distribution, Normal distribution, properties of normal distribution, Standard normal distribution, Relationship between two variables, correlation coefficient, regression coefficients, regression equation, regression line, determination coefficient, Sampling distributions, sampling distribution of means, sample distribution the differences between two means, sampling distribution of proportions, sampling distribution of differences between two proportions, sampling distribution of correlation, Hypothesis testing, hypotheses, test statistics, Type I and Type II errors, one- and two tailed tests, Z-distribution, hypothesis testing: a single population mean, the difference between two population means, a single population proportion, t-distribution, hypothesis testing: a single population mean, the difference between two population means, the difference between two population proportions, correlation coefficient, Confidence interval, confidence interval for population mean, Chi-square distribution, test of homogeneity, tests of goodness-of-Fit, test of independence
Learning Outcomes 1) The students learn that the data collection from all the individuals in a population requires a lot of costs and time and understands that it is necessary to study on a random sample taken from the population
2) The students understand that it needs to study on a random sample to obtain reliable results
3) The students learn that the values of population, called parameters, are estimated from the sample data and are called statistic
4) They learn to examine the association between two variables of drugs being studied and to interpret the results
5) The students learn that the values of population, called parameters, are estimated from the sample data and are called statistic
6) The students learn that when hypothesis is stated, it requires to carry out an experiment to collect data and to evaluate the hypothesis using the collected data and to perform a hypothesis control and to evaluate and interpret the results

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week The basic concepts of statistics, collection of data, type of data (continuous and discrete) and summarizing Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
2. Week Descriptive statistics, Measures of central tendency (arithmetic mean, median, mode, geometric mean, harmonic mean) Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
3. Week Measures of dispersion (range, variance, standard deviation, coefficient of variation) Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
4. Week Relationship between two variables, correlation coefficient, regression coefficients, regression equation, regression line, determination coefficient, Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
5. Week Relationship between two variables, correlation coefficient, regression coefficients, regression equation, regression line, determination coefficient, Lecture; Question Answer; Problem Solving; Discussion; Case Study
Brainstorming
Homework
6. Week Statistical distributions, Binomial distribution, calculation of the probabilities of events properties of the binomial distribution, parameters of the Binomial distribution, shape of the binomial distribution, Poisson distribution, calculation of the probabilities of events, properties of the Poisson distribution, parameters of the Poisson distribution, shape of the Poisson distribution Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
7. Week Normal distribution, properties of normal distribution, calculation of the probabilities, normal distribution applications Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
8. Week Sampling distributions, sampling distribution of means, sampling distribution of differences between two means, sampling distribution of proportions Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
9. Week Hypothesis testing, hypotheses, test statistics, Type I and Type II errors, one- and two tailed tests Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
10. Week Z-distribution, hypothesis testing: a single population mean, the difference between two population means, a single population proportion Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
11. Week t-distribution, hypothesis testing: a single population mean, the difference between two population means, and correlation coefficient Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
12. Week Paired t-test, confidence interval, confidence interval for population mean Lecture; Question Answer; Problem Solving; Case Study
Opinion Pool
Homework
13. Week Chi-square distribution, test of homogeneity, tests of goodness-of-Fit, test of independence Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework
14. Week Chi-square distribution, test of homogeneity, tests of goodness-of-Fit, test of independence Lecture; Question Answer; Problem Solving; Discussion; Case Study
Opinion Pool
Homework

Sources Used in This Course
Recommended Sources
1. KESİCİ T. ve KOCABAŞ Z. (2007). Biyoistatistik (İkinci Baskı). Ankara Üniversitesi Eczacılık Fakültesi Yayın No: 94
10. SNEDECOR, W. and COCHRAN W. G. 1980. Statistical Methods. Seventh Edition. The Iowa state University Press, Ames, Iowa, USA.
2. APAYDIN, A., KUTSAL, A. ve ATAKAN, C. 1994. Uygulamalı İstatistik. Ankara
3. DANIEL, W. W. 1995. Biostatistics. A Foundation for Analysis in the Health Sciences. Sixth Edition. John Willey & Sons, Inc. New York
4. BARNETT, V. and LEWİS, T. 1978. Outliers in Statistical Data. John Wiley & Sons Ltd., Great Britain.
5. DÜZGÜNEŞ, O., KESİCİ, T., KAVUNCU, O. ve GÜRBÜZ, F. 1987. Araştırma ve Deneme Metodları. (İstatistik Metodları II). Ankara Üniversitesi, Ziraat Fakültesi Yayınları: 1021, Ders Kitabı: 295. Ankara.
6. DÜZGÜNEŞ, O., KESİCİ, T. ve GÜRBÜZ, F. 1993. İstatistik Metodları. İkinci Baskı. Ankara Üniversitesi, Ziraat Fakültesi Yayınları: 1291, Ders Kitabı: 369. Ankara.
7. FREUND, J. E. 1971. Mathematical Statistics. Second Edition. Prentice-Hall, Inc., Englewood Cliffs, New Jersey.
8. MENDENHALL, W. and SCHEAFFER, R. L. 1973. Mathematical Statistics and Applications. Wadsworth publishing Company, Inc. Belmont, California, USA.
9. PETERSON, G. R. 1985. Design and Analysis of Experiments. Marcel Dekker, Inc., New York and Basel.

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3DK4DK5DK6
PY15000000
PY25000000
PY35000000
PY45000000
PY55000000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 2
Homework 7 3
Midterm Exam 1 1.5
Time to prepare for Midterm Exam 1 5
Final Exam 1 1.5
Time to prepare for Final Exam 1 5
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
Quick Access Hızlı Erişim Genişlet
Course Information