Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
PHARMACEUTICAL CHEMISTRY III PHM4001 7. Semester 2 + 0 2.0 3.0

Prerequisites None

Language of Instruction English
Course Level Bachelor's Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Ali Hakan GÖKER
Assistants Sibel SÜZEN
Goals Aim of this course is to give knowledge and skills on synthesis and mechanisms of all the drugs that are related to autonomic nervous system and cardiovascular diseases. This course has also purpose and content of education to guide patients in drug treatment and to ensure the patients awareness about drugs.
Course Content In this course formula, nomenclature, general physicochemical properties, general synthetic pathways, metabolism, stability, general chemical analysis, structure-activity relationships and therapeutic uses of cholinergic, parasympathomimetic, anticholinesterase, parasympatholytic, antianginal, antiaritmic, antihyperlipidemic, anticoagulant, thrombolytic and antiplatelet drugs are taught.
Learning Outcomes 1) Designs and synthesises medicines that are effective in autonomic nervous system and cardiovascular system, inteprets the pharmacological effects of molecular structure
2) Informs patients about drugs related to autonomic nervous system and cardiovascular system
3) Otonom Sinir Sistemi ve Kardiyovasküler Sistemle ilgili ilaç araştırma ve geliştirme (AR-GE) çalışmalarını yürütme yetisine sahiptir.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week General information of autonomic nervous system, - Adrenergic receptors and pharmacological functions Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
2. Week Alpha and beta adrenergic agonist drugs Lecture; Question Answer
Colloquium
Problem Based Learning
Homework Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
3. Week Central nervous system stimulants and anorexigenics Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
4. Week Alpha and beta adrenergic receptor bloker drugs Lecture; Question Answer
Colloquium
Problem Based Learning
Homework Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
5. Week Alpha and beta adrenergic receptor bloker drugs Lecture; Question Answer
Colloquium
Problem Based Learning
Homework Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
6. Week Cholinergic drugs Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
7. Week Parasympatholytic compounds, cholinergic bloker drugs Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
8. Week Compounds effected in the cardiovascular system - introduction - Antianginal compounds Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
9. Week Calcium antagonists Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
10. Week Antiaritmic compounds Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
11. Week Antihypertensive compounds Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
12. Week Compounds effect on Renin-Angiotensin-Aldosteron system - Angiotensin Converting Enzyme (ACE) inhibitors -Angiotensin Receptor Antagonists Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
13. Week Compounds used for hyperlipoproteinemia Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
14. Week Anticoagulant, thrombolytic and antithrombolytic compounds Lecture; Question Answer
Colloquium
Problem Based Learning
Activity (Web Search, Library Work, Trip, Observation, Interview etc.)

Sources Used in This Course
Recommended Sources
Burger's Medicinal Chemistry, Drug Discovery and Development 7th Edition, 8 Volume Set ISBN: 978-0-470-27815-4 September 2010
Farmasötik Kimya Hacettepe Üniversitesi Yayınları ISBN: 978-975-491-171-8 3. Baskı, Aralık 2013
Foye's Principles of Medicinal Chemistry Publication Date: March 8, 2012 ISBN-10: 1609133455 ISBN-13: 978-1609133450 Edition: Seventh, North American Edition
Pharmaceutical Chemistry, David G. Watson (Author) Publication Date: February 18, 2011 ISBN-10: 0443072329 ISBN-13: 978-0443072321 Edition: 1
Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry Publication Date: March 2, 2010 ISBN-10: 0781779294 ISBN-13: 978-0781779296 Edition: Twelfth, North American Edition

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25004
PY35000
PY45000
PY55000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 2
Presentation (Including Preparation Time) 2 4
Project (Including Preparation and presentation Time) 2 3
Final Exam 1 10
Time to prepare for Final Exam 1 5
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information