Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
PHARMACEUTICAL TOXICOLOGY PRACTICE II PHM4002 8. Semester 0 + 4 2.0 4.0

Prerequisites None

Language of Instruction English
Course Level Bachelor's Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Tülay ÇOBAN
Assistants Ahmet Oğuz ADA
İlker ATEŞ
Aylin ÜSTÜNDAĞ
Özge ÜLKER
Binay CAN EKE
Halit Sinan SÜZEN
Yalçın DUYDU
SEZEN YILMAZ SARIALTIN
Goals Determination of blood ethyl alcohol; Screening of cyanide and carbon monoxide; Isolation and identification experiments of barbiturates by liquid-liquid extraction; Lead analysis by ditizone extraction method; Delta-aminolevulinic acid (ALA) assay in urine for evaluation of lead exposure; Toxicological analyzes in food products; Toxicological analyzes on water, milk, daily foods and edible oil samples; Chromatographic separation and quantitation methods applied in toxicology; Identification of phosphorous insecticides by thin layer chromatography; To give information about analysis of narcotics by thin layer chromatography
Course Content Determination of blood ethyl alcohol; Screening of cyanide and carbon monoxide; Isolation and identification experiments of barbiturates by liquid-liquid extraction; Lead analysis by ditizone extraction method; Delta-aminolevulinic acid (ALA) assay in urine for evaluation of lead exposure; Toxicological analyzes in food products; Toxicological analyzes on water, milk, daily foods and edible oil samples; Chromatographic separation and quantitation methods applied in toxicology; Identification of phosphorous insecticides by thin layer chromatography; Analysis of narcotics by thin layer chromatography
Learning Outcomes 1) "Toxicological knowledge of natural and synthetic raw materials and their toxicological analysis and evaluation in the process from production to consumption."
2) Could consider the safe effects of the natural and synthetic chemicals (drugs,cosmetics and nutrient contaminants) to the human and environment health and develop suggestions
3) Have the ability to research a study related to population health and make a contribution to the carrier development

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week General expression Question Answer; Discussion
Brainstorming
Case Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
2. Week Determination of ethanol in blood Case Study
Brainstorming; Colloquium
Case Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
3. Week Determination of cyanide in blood Lecture
Brainstorming
Problem Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
4. Week Determination of carbonmonoxide in blood Problem Solving
Brainstorming
Case Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
5. Week Extraction and characterization tests for barbiturates Question Answer
Brainstorming
Case Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
6. Week Lead analysis by dithizone extraction Question Answer
Brainstorming
Problem Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
7. Week Determination of Delta aminolevulinic acid in urine for the assessement of lead exposure Lecture; Question Answer
Brainstorming
Project Based Learning; Problem Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
8. Week Determination of organophosfate insecticides by thin layer chromatography Question Answer
Brainstorming
Case Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
9. Week Determination of narchotics by thin layer chromatography Lecture
Brainstorming
Project Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
10. Week Analysis of Decay Products and Non-Legal Additives of Oils Question Answer
Brainstorming
Problem Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
11. Week Analyses of milk and milk products I Lecture
Brainstorming
Project Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
12. Week Analyses of milk and milk products 2 Question Answer
Brainstorming
Case Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
13. Week Toxicologic analyses in water 1 Question Answer
Brainstorming
Case Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
14. Week Toxicologic analyses in water 2 Lecture
Brainstorming
Case Based Learning 		Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)

Sources Used in This Course
Recommended Sources
Casarett&Doull’s Toxicology: The Basic Science of Poisons Ed: Klaassen CD, McGraw-Hill Medical Publishing Division. New York-Toronto, 2001

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25000
PY35000
PY45000
PY55000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Homework 2 10
Presentation (Including Preparation Time) 2 10
Midterm Exam 1 2
Time to prepare for Midterm Exam 10 2
Final Exam 1 2
Time to prepare for Final Exam 14 2
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload