Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
SPESIFIC TOXIC EFFECTS ATO5602011 3 + 0 3.0 6.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors
Assistants
Goals Learning of mutagenesis, carcinogenesis and teratogenesis which are caused by various factors, mainly chemicals.
Course Content Agents that cause mutations, mutagenesis mechanisms, mutagenicity tests, cancer causing agents, cancer development mechanisms, classification of carcinogens, carcinogenicity tests, teratogenic agents, teratogenesis mechanisms, teratogenicity tests.
Learning Outcomes 1) Learns the mechanisms and importance of chemical mutagenesis.
2) Learns the mechanisms and importance of chemical carcinogenesis.
3) Learns the mechanisms and importance of chemical teratogenesis.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Transcription, translation and replication Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
2. Week Chemical mutagenesis Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
3. Week Factors causing mutation Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
4. Week Mechanisms of mutagenesis Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
5. Week Micro and macrolezions Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
6. Week Chemical carcinogenesis I Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
7. Week Chemical carcinogenesis II Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
8. Week Factors causing cancer Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
9. Week Mechanisms of carcinogenesis Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
10. Week Mutagenicity and carcinogenicity detection methods Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
11. Week Teratogenesis Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
12. Week Teratogenic factors Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
13. Week Mechanisms of teratogenesis Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)
14. Week Teratogenic drugs Lecture; Question Answer
Brainstorming; Opinion Pool
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Casarett & Doull's Toxicology: The Basic Science of Poisons, Curtis Klaassen, McGraw-Hill Education / Medical; 8 edition, June 19, 2013.
Essential Concepts in Toxicogenomics, Donna L. Mendrick (Editor),‎ William B. Mattes (Editor), Humana Press, 2008.
Essential Concepts in Toxicogenomics, Donna L. Mendrick (Editor),‎ William B. Mattes (Editor), Humana Press, 2008.
Mechanisms of Environmental Mutagenesis-Carcinogenesis, A. Kappas, Springer; November 7, 2012.
Toxicogenomics: A Powerful Tool for Toxicity Assessment, Edited by S. C. Sahu 2008 John Wiley & Sons, Ltd., 2008 ISBN: 978-0-470-51823-6

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY45555
PY55555
PY65555
PY75555
PY85555
PY95555
PY105444
PY115555

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 3
Work Hour outside Classroom (Preparation, strengthening) 14 2
Homework 1 14
Presentation (Including Preparation Time) 14 2
Midterm Exam 1 2
Time to prepare for Midterm Exam 7 2
Final Exam 1 2
Time to prepare for Final Exam 14 4
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload