Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
BIOCHEMISTRY ALVS103 1. Semester 0 + 0 0 5.0

Prerequisites None

Language of Instruction Turkish
Course Level Associate's Degree
Course Type Compulsory
Mode of delivery Face to face
Course Coordinator
Instructors ANKUZEF ANKUZEF
Assistants
Goals Biochemistry deals with striking properties of living organisms that contains thousands of various biological molecules. To describe the biochemical terms, the structures, mechanisms and properties of amino acids, protein and carbohydrates.
Course Content Functional groups, biomolecules, the structures, functions and varieties of amino acids, primary, secondary, tertiary and quarternary structures and functions of proteins, the chemistry of carbohyrates and glycobiology, metabolism of carbohydate, glycolysis, pathway of pyruvate, pentoseve önemi, karbohidrat sentesi, karbohidrat sentez ve yıkımının kontrolü
Learning Outcomes 1) Learn the peptide secondary structures of the proteins by utilizing the phi and psi angle and the Ramachandran graphs.
2) Explain the biochemical structures of amino acids to know the secondary structures of peptides
3) Primary, secondary, tertiary and quartarnary structures of proteins have been recognized
4) It clearly and precisely indicates that metabolic pathway can be controlled by the enzymes which catalyze the irreversible reactions

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Functional Groups Lecture; Question Answer; Problem Solving; Discussion; Case Study
Brainstorming; Colloquium
Problem Based Learning
Homework Presentation (Including Preparation Time)
Introduction to biochemistry, chemical bonds, disulhate brige, hydrophilic and hydrophobic interactions functional groups etc. Lecture; Question Answer; Discussion
Brainstorming; Colloquium
Problem Based Learning
Homework Presentation (Including Preparation Time)
2. Week Introduction to amino acids, peptide and proteins; formules of amino acid, pKa values, isoelectric points and its importance etc. Lecture; Question Answer; Problem Solving; Discussion; Case Study
Brainstorming; Colloquium
Problem Based Learning
Homework Presentation (Including Preparation Time)
3. Week Secondary structures of proteins; the structure and feature of peptide bond, Ramachandran graphs, α-helix β-turn and β-twisted structure Lecture; Question Answer; Discussion; Case Study
Brainstorming; Colloquium
Project Based Learning; Problem Based Learning
Homework Presentation (Including Preparation Time)
4. Week Tertiary structure of proteins; fibrous proteins, α-keratine, silk fibrion and collogen Lecture; Question Answer; Discussion; Case Study
Brainstorming; Colloquium
Project Based Learning; Problem Based Learning
Homework Presentation (Including Preparation Time)
5. Week Functions of proteins; some examples of globular proteins such as myoglobin and hemoglobine Lecture; Question Answer; Discussion; Case Study
Brainstorming; Colloquium
Project Based Learning; Problem Based Learning
Homework Presentation (Including Preparation Time)
6. Week Carbohydrate and glycobiology; monosaccharides, structures of aldoses and ketoses, enantiomers, diasteriomers, epimers, hemiasetal and hemiketal Lecture; Discussion; Case Study
Brainstorming; Colloquium
Project Based Learning; Problem Based Learning
Homework Presentation (Including Preparation Time)
7. Week Polysaccharides, glucoconjugates, extracellular matrix heteropolysaccharides and their biochemical structures Lecture; Question Answer; Discussion
Brainstorming
Brain Based Learning
Homework Presentation (Including Preparation Time)
8. Week MIDTERM Question Answer
Colloquium
Problem Based Learning
Practice (Teaching Practice, Music/Musical Instrument Practice, Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice)
9. Week Glycolysis: carbohydrate oxidation, all step of biochemical reactions and the functions of related enzymes Lecture; Question Answer; Discussion
Brainstorming; Colloquium
Project Based Learning; Problem Based Learning
Homework Presentation (Including Preparation Time)
10. Week Glycolysis (Continue) Lecture; Question Answer; Discussion
Colloquium
Project Based Learning; Problem Based Learning
Homework Presentation (Including Preparation Time)
11. Week Fates of pyruvate, gluconeogenesis Lecture; Question Answer; Discussion
Brainstorming; Colloquium
Problem Based Learning
Homework Presentation (Including Preparation Time)
12. Week Pentose phosphate pathway of gulcose oxidation (oxidative and nonoxidative phase) Lecture; Question Answer; Discussion
Colloquium
Problem Based Learning
Homework Presentation (Including Preparation Time)
13. Week Principles of metabolic regulations: glucose and glycogen Lecture; Question Answer; Discussion
Colloquium
Problem Based Learning
Homework Presentation (Including Preparation Time)
14. Week Principles of metabolic regulations: glucose and glycogen (continue) Lecture; Question Answer; Discussion
Colloquium
Problem Based Learning
Homework Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Harper’s Illustrated Biochemistry, R. K. Murray, D. K. Granner, P. A. Mayes, V. W. Rodwell, Lange Medical Books/McGraw-Hill Medical Publishing Division, 2003.
Basic Concepts in Biochemistry, A Student’s Survival Guide, H. F. Gilbert, McGraw-Hill Health Proffesions Division, 2000.
Biochemistry, J. M. Berg, J. L.Tymoczko, L. Stryer W. H. Freeman and Company and Sumanas, Inc, 2005.
Color Atlas of Biochemistry, J. Koolman, K. H. Roehm, Georg Thieme Verlag, 2005.
Lehninger Biyokimyanın İlkeleri, 5. baskıdan çeviri; David L. Nelson ve Michael M. Cox, Çeviri Editörü: Prof. Dr. Y.Murat Elçin, Palme Yayıncılık, 2013
Principles of Biochemistry, H. R. Horton, L. A. Moran, K. G. Scrimgeour, M. D. Perry, J. D. Rawn, Pearson Prentis Hall, 2006.

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3DK4
PY155555
PY255555
PY355555
PY455555
PY555555

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 5
Homework 2 2
Midterm Exam 1 1
Time to prepare for Midterm Exam 1 12
Final Exam 1 2
Time to prepare for Final Exam 1 24
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information