Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
ORGANIC CHEMISTRY III KİM317 5. Semester 4 + 0 4.0 5.0

Prerequisites None

Language of Instruction English
Course Level Bachelor's Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Özgen ÖMÜR PEKEL
Assistants
Goals The aim of this course is to acquire the basic knowledge about the concept of aromaticity, aromatic, heterocyclic and pericyclic compounds, their properties, obtaining and reactions, spectroscopic methods for determination of structures of organic compounds, carbohydrates, amino acids and proteins.
Course Content Aromatic Compounds: Aromaticity concept, nomenclature, physical and chemical properties, preparation and reactions. Heterocyclic Compounds: Properties and nomenclature of aromatic heterocycle compounds, nucleophilic substitution in pyridine, quinoline and isoquinoline, electrophilic substitution in pyrrole ring, porphyrins. Pericyclic reactions, their properties, classification, Diels-Alder and electrocyclic reactions, sigmotropic rotations, symmetry-permissive and symmetry-prohibited reactions. Spectroscopic Methods in Organic Chemistry: Ultraviolet spectroscopy (U.V., ultraviolet), infrared (IR, infrared) spectroscopy, mass spectroscopy, Nuclear Magnetic Resonance (NMR) spectroscopy, spectroscopic methods. Carbohydrates, amino acids and proteins: structure of monosaccharides, disaccharides, artificial sweeteners, polysaccharides, biosynthetic sugars, amino acids and proteins, synthesis of proteins, analysis of polypeptides and proteins, classification of proteins, introduction of enzymes, serine proteases and hemoglobin.
Learning Outcomes 1) Explains the structures of organic compounds according to the molecular orbital theory.
2) Classifies the organic compounds according to their basic functional group.
3) Names organic compounds according to internationally accepted rules
4) Recognises the isomeric species in organic chemistry.
5) Knows the physical and chemical properties of organic compounds.
6) Explains the properties that an organic compound must have in order to be aromatic.
7) Understands the synthesis of organic compounds.
8) Knows the reactions of organic compounds containing functional groups.
9) Understands the importance of organic compounds in daily life.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Aromatic Compounds: Aromaticity concept, nomenclature, physical and chemical properties, syntheses, Hückel rule, aromatic, antiaromatic and nonaromatic compounds. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
2. Week Aromatic Compounds: Other aromatic compounds, heterocyclic compounds, reactions of aromatic compounds: Electrophilic and nucleophilic substitution and other reactions, effect of substituents on reactivity and orientation in electrophilic aromatic substitution, halogen substituents: efficiency reducing ortho-, para- directing groups. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
3. Week Aromatic Compounds: Activity reducing groups: meta-orientation, inductive and resonance effects, orientation theory, ortho- and para-orientation effects and activities of alkyl benzenes, side chain reactions of alkyl benzenes, alkenyl benzenes, synthetic applications. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
4. Week Aromatic Compounds: Orientation in disubstituted benzenes, aromatic nucleophilic substitution reactions (SNAr), reduction of aromatic compounds, Wurtz-Fittig reaction, related sample questions and solutions (applications), phenols and derivatives, fused ring aromatic compounds. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
5. Week Heterocyclic Compounds: Properties and nomenclature of aromatic heterocycle compounds, nucleophilic substitution in pyridine, quinoline and isoquinoline, electrophilic substitution in pyrrole ring, porphyrins. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
6. Week Heterocyclic Compounds: Properties and nomenclature of aromatic heterocycle compounds, nucleophilic substitution in pyridine, quinoline and isoquinoline, electrophilic substitution in pyrrole ring, porphyrins. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
7. Week Pericyclic Reactions: General properties of pericyclic reactions, classification, boundary orbitals in alkene and alkenyl systems, Diels-Alder cyclocondensation reactions, electrocyclic reactions, sigmotropic rotations, symmetry permissive and symmetry prohibited reactions. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
8. Week Pericyclic Reactions: General properties of pericyclic reactions, classification, boundary orbitals in alkene and alkenyl systems, Diels-Alder cyclocondensation reactions, electrocyclic reactions, sigmotropic rotations, symmetry permissive and symmetry prohibited reactions. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
9. Week Structural Analysis of Organic Compounds:Spectroscopic Methods: Materials and light, ultraviolet spectroscopy (U.V, ultraviolet), infrared (IR, infrared) spectroscopy, mass spectroscopy (MS), Nuclear Magnetic Resonance (NMR) spectroscopy, spectroscopic methods. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
10. Week Structural Analysis of Organic Compounds:Spectroscopic Methods: Materials and light, ultraviolet spectroscopy (U.V, ultraviolet), infrared (IR, infrared) spectroscopy, mass spectroscopy (MS), Nuclear Magnetic Resonance (NMR) spectroscopy, spectroscopic methods. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
11. Week Structural Analysis of Organic Compounds:Spectroscopic Methods: Materials and light, ultraviolet spectroscopy (U.V, ultraviolet), infrared (IR, infrared) spectroscopy, mass spectroscopy (MS), Nuclear Magnetic Resonance (NMR) spectroscopy, spectroscopic methods. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
12. Week Structural Analysis of Organic Compounds:Spectroscopic Methods: Exercises. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
13. Week Carbohydrates, Amino acids and Proteins: Structure and synthesis of monosaccharides, glycoside formation, classification and reactions of monosaccharides, disaccharides, artificial sweeteners, polysaccharides, other sugars with biological importance, amino acids and proteins, synthesis and analysis of polypeptides and proteins and amino acid sequences, classification of proteins, Introduction to enzymes, serine proteases, hemoglobin. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
14. Week Carbohydrates, Amino acids and Proteins: Structure and synthesis of monosaccharides, glycoside formation, classification and reactions of monosaccharides, disaccharides, artificial sweeteners, polysaccharides, other sugars with biological importance, amino acids and proteins, synthesis and analysis of polypeptides and proteins and amino acid sequences, classification of proteins, Introduction to enzymes, serine proteases, hemoglobin. Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Organik Kimya Yaşamın Kalbi, Prof.Dr. Yılmaz Yıldırır (Yazar). Bilim Kitap Kırtasiye Ltd.Şti. Ağustos, 2014.
Organik Kimya Yenilenmiş 7.baskı, Celal Tüzün, Palme Yayıncılık. Ankara (1996).
Organic Chemistry 7th Edition, T. W. Graham Solomons, Craig B. Fryhle 11th Ed. 2013.
Organic Chemistry,John E. McMurry, 1999.
Organik Kimya (11. Basım'dan Çeviri) Graham Solomons , Graig Fryhle, S.A Snyder, Çeviri Editörü: Cavit Uyanık (Kocaeli Üniv.), Literatür yayıncılık, dağıtım, San. ve Tic. Ltd. Şti.2016.
Organik Kimya- P. Vollhardt and N.Schore, 6.baskıdan çeviri; Editörler: Tahsin Uyar ve Fatma Sevin Düz, Palme Yayıncılık, 2011.
Organik Kimya, Ralph J Fessenden and Joan S Fessenden and Marhall W.Logue. Çeviri Editörü: Prof. Dr. Tahsin Uyar. Güneş Kitapevi Ltd. Şti. Ankara, 1. Baskı (2001).
Organik Tepkime Mekanizmaları, Celal Tüzün, 3.baskı. Palme Yayınevi, Ankara (2007).

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3DK4DK5DK6DK7DK8DK9
PY15000500000
PY25000000000
PY35000000000
PY45000000000
PY55000005000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 4
Work Hour outside Classroom (Preparation, strengthening) 14 3
Homework 1 8
Midterm Exam 2 1.5
Time to prepare for Midterm Exam 2 10
Final Exam 1 1.5
Time to prepare for Final Exam 1 20
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information