Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
PEPTIDE AND PROTEINS: PHYSICAL CHARACTERISTICS AND STABILITIES 34233005 2 + 0 2.0 4.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery Explanation of the theoretical course into PowerPoint presentations every week, discussed the subject on literature reviews on specific examples with participation of students.
Course Coordinator
Instructors Asuman BOZKIR
Assistants Umut Can ÖZ
Goals Definition of peptide and proteins, explanation of structural features, teaching the physical and chemical stability behavior of peptide and protein structured active substances. Teaches regulatory applications of stability problems in peptide and protein formulations (microspheres, nanoparticles, liposomes, microemulsions, emulsion and so on).
Course Content Evaluation of stability behaviour of peptide protein including formulations and make assessments on the development of the most stable formulation design.
Learning Outcomes 1) Learning of definition and structural properties of peptides and proteins.
2) Evaluation of physical and chemical stability behaviours of peptide and protein drugs.
3) Makes regulatory recommendations to stability problems of peptide and protein formulations (microsphere, nanoparticle, liposome, microemulsion, emulsion ...)

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Definition of peptides and proteins Lecture
Brainstorming
Problem Based Learning 		Homework
2. Week Explanation of the structural features of peptides and proteins Lecture
Brainstorming
Problem Based Learning 		Homework
3. Week Determination of physical and chemical stability behaviour of peptide and protein drugs. Lecture
Brainstorming
Problem Based Learning 		Homework
4. Week Determination of physical stability behaviour of peptide and protein drugs Lecture
Brainstorming
Problem Based Learning 		Homework
5. Week Determination of chemical stability behaviour of peptide and protein drugs. Lecture
Brainstorming
Problem Based Learning 		Homework
6. Week Determination of chemical stability behaviour of peptide and protein drugs. Lecture
Brainstorming
Problem Based Learning 		Homework
7. Week Stability problems in peptide and protein formulations Lecture
Brainstorming
Problem Based Learning 		Homework
8. Week Midterm exam Question Answer
9. Week Regulatory applications of stability problems in peptide and protein microsphere formulations Lecture
Brainstorming
Problem Based Learning 		Homework
10. Week Regulatory applications of stability problems in peptide and protein nanoparticle formulations Lecture
Brainstorming
Problem Based Learning 		Homework
11. Week Regulatory applications of stability problems in peptide and protein liposome formulations Lecture
Brainstorming
Problem Based Learning 		Homework
12. Week Regulatory applications of stability promlems in peptide and protein microemulsion formulations Lecture
Brainstorming
Problem Based Learning 		Homework
13. Week Regulatory applications of stability problems in peptide and protein emulsion formulations Lecture
Brainstorming
Problem Based Learning 		Homework
14. Week Regulatory applications of stability problems in peptide and protein formulations Lecture
Brainstorming
Problem Based Learning 		Homework
15. Week Regulatory applications of stability problems in peptide and protein formulations Lecture
Brainstorming
Problem Based Learning 		Homework
16. Week Final Exam Question Answer

Sources Used in This Course
Recommended Sources
Canefe K., Bozkir, A., The Limitations and General Definitations on the Stability Investigations of Drugs under Different Climatic Conditions, Pharmacia, 31(3),1991
Canefe K., Bozkir, A., The Limitations and General Definitations on the Stability Investigations of Drugs under Different Climatic Conditions, Pharmacia, 31(3),1991
Carstensen, J.T., Pharmaceutics of Solids and Solid Dosage Forms, John&Willey Sons, 1977
Carstensen, J.T., Pharmaceutics of Solids and Solid Dosage Forms, John&Willey Sons, 1977
Carstensen, J.T., Rhodes, C.T., Drug Stability, Marcel-Dekker Inc, New York, 2000
Carstensen, J.T., Rhodes, C.T., Drug Stability, Marcel-Dekker Inc, New York, 2000
Dittert, L.W., American Pharmacy, Sprowls, 7th edd., Lippincot Comp, 1974
Dittert, L.W., American Pharmacy, Sprowls, 7th edd., Lippincot Comp, 1974
Sambrook, J., Fritsch, E.F., Maniatis, T., Molecular Cloning: a Laboratory Manual, Cold Spring Harbor Lab. Press, 1989.
Sambrook, J., Fritsch, E.F., Maniatis, T., Molecular Cloning: a Laboratory Manual, Cold Spring Harbor Lab. Press, 1989.
Woodbury, C.P., Pharmaceutical Biotechnology: fundmentals and essentials, Interpharm Press, 1992.
Woodbury, C.P., Pharmaceutical Biotechnology: fundmentals and essentials, Interpharm Press, 1992.

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25000
PY35000
PY45000
PY55055

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 5
Midterm Exam 1 2
Time to prepare for Midterm Exam 1 10
Final Exam 1 2
Time to prepare for Final Exam 1 10
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
Quick Access Hızlı Erişim Genişlet
Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload