Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
POLYMER SCIENCE 34234001 3 + 0 3.0 9.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery Lecture, question and answer, discussion
Course Coordinator
Instructors
Assistants
Goals In systems that release controlled active substances, natural and synthetic polymers are used both as carrier materials and to control the release of active substance. It is aimed to define synthesis, polymerization methods and properties of these materials which are widely used in our field and the methods for examining these properties.
Course Content Pharmaceutical applications of polymers History and definitions Polymer synthesis and structures Homopolymers and copolymers Polymerization methods Polymers include additives, cross-linkers, plastisers and fillers Molecular weights and distribution and determination methods of polymers Mechanical, electrical, optical and thermal properties of polymers Structural properties of polymers and glass-rubber transition of polymers Methods for the analysis of thermal properties of polymers Preparation of polymer solutions, gel formation and phase separation Classification of polymers and diffusion from polymeric systems Properties of polymers as biomaterials
Learning Outcomes 1) Know definitions related to polymers.
2) Know the synthesis and polymerization methods of polymers.
3) Know the choice of polymers to be used in the preparation of drugs.
4) Know the effect of polymer properties on active substance release.
5) Polymeric drug delivery systems are capable of quality control in terms of the polymers used.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Pharmaceutical applications of polymers Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
2. Week History and definitions Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
3. Week Polymer synthesis and structures Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
4. Week Homopolymers and copolymers Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
5. Week Polymerization methods Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
6. Week Polymers include additives, cross-linkers, plastisers and fillers Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
7. Week Molecular weights and distribution and determination methods of polymers Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
8. Week Molecular weights and distribution and determination methods of polymers Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
9. Week Mechanical, electrical, optical and thermal properties of polymers Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
10. Week Structural properties of polymers and glass-rubber transition of polymers Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
11. Week Methods for the analysis of thermal properties of polymers Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
12. Week Preparation of polymer solutions, gel formation and phase separation Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
13. Week Classification of polymers and diffusion from polymeric systems Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
14. Week Properties of polymers as biomaterials Lecture
Brainstorming
Problem Based Learning
Presentation (Including Preparation Time)
15. Week Homework presentation Lecture

Homework
16. Week Final exam Question Answer


Sources Used in This Course
Recommended Sources
"Joseph R. Robinson and Vincent H.L. Lee, Controlled Drug Delivery - Fundamentals and Applications, Marcel Dekker, Inc., 1987. " Alfred Martin, Pilar Bustamante and A.H.C. Chun, Physical Pharmacy, Lea&Febiger, 1993. Tom Sam and Jasper Fokkens (Eds.), Innovations in Drug Delivery: Impact on Pharmacotherapy, CIP-gegevens Koninklijke Bibliotheek, 1996. Ayla Gürsoy, Erhan Pişkin, Betül A. Dortunç and Nicholas A. Peppas, Kontrollu İlaç Serbestleştiren Sistemler, Tekno Grafik&Ada Ofset,1989. Ayla Gürsoy (Ed.), Kontrollu Salım Sistemleri, Elma Bilgisayar BasımAmbalaj San. Tic. Ltd. Şti., 2002. Waleed S.W. Shalaby and Haesun Park, Biodegradable Hydrogels for Drug Delivery, Technomic Publishing Company, Inc.,1993. Nilüfer Yüksel,Teoman Tinçer and Tamer Baykara, The interaction between Nicardipine hydrochloride and polymeric microspheres for a controlled release system, Int. J.Pharm., 1996. "Introduction to Physical Polymer Science, by L.H. Sperling ISBN 0-471-70606-X Copyright © 2006 by John Wiley & Sons, Inc."

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 3
Work Hour outside Classroom (Preparation, strengthening) 14 13
Homework 1 1
Presentation (Including Preparation Time) 1 15
Report (Including Preparation and presentation Time) 1 10
Final Exam 1 1
Time to prepare for Final Exam 1 10
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information