Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
PEPTIDE AND PROTEINS: PHYSICAL CHARACTERISTICS AND STABILITIES (PRACTICE) 34234008 0 + 6 3.0 6.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery Learning the usage of special techniques for the analysis of protein samples, evaluation of the stability test conditions and parameters and interpretation of results.
Course Coordinator
Instructors
Assistants
Goals Definition of peptide and protein, explanation of structural features, teaching of chemical and physical stability behavior of the active substance in the protein structure. Learning application stability problems of peptide and protein formulations in microspheres, nanoparticles, liposomes, microemulsions, emulsion and etc.
Course Content In order to realize the structural analysis of peptide and proteins use of spesifical techniques, examining these applications on the sample protein and evaluation of stability behaviour.
Learning Outcomes 1) Working for analysis and stability of peptide and protein active ingredient
2) To investigate the stability behavior in step of preformulation formulation of peptides and proteins (microspheres, nanoparticles , liposomes, microemulsions, emulsion, etc.)
3) Learning application stability problems of peptide and protein formulations in microspheres, nanoparticles, liposomes, microemulsions, emulsion and etc.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Analysis and stability of peptide and protein active ingredient Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
2. Week To investigate the stability behavior in step of preformulation formulation of peptides and proteins Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
3. Week project work Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
4. Week project work Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
5. Week project work Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
6. Week project work Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
7. Week project work Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
8. Week midterm exam Question Answer

 Homework
9. Week project work Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
10. Week project work Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
11. Week project work Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
12. Week project work Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
13. Week evaluating of project output Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
14. Week evaluating of project output Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
15. Week evaluating of project output Lecture
Brainstorming
Problem Based Learning 		Presentation (Including Preparation Time)
16. Week exam Question Answer

 Homework

Sources Used in This Course
Recommended Sources
Canefe K., Bozkir, A., The Limitations and General Definitations on the Stability Investigations of Drugs under Different Climatic Conditions, Pharmacia, 31(3),1991
Canefe K., Bozkir, A., The Limitations and General Definitations on the Stability Investigations of Drugs under Different Climatic Conditions, Pharmacia, 31(3),1991
Carstensen, J.T., Pharmaceutics of Solids and Solid Dosage Forms, John&Willey Sons, 1977
Carstensen, J.T., Pharmaceutics of Solids and Solid Dosage Forms, John&Willey Sons, 1977
Carstensen, J.T., Rhodes, C.T., Drug Stability, Marcel-Dekker Inc, New York, 2000
Carstensen, J.T., Rhodes, C.T., Drug Stability, Marcel-Dekker Inc, New York, 2000
Dittert, L.W., American Pharmacy, Sprowls, 7th edd., Lippincot Comp, 1974
Dittert, L.W., American Pharmacy, Sprowls, 7th edd., Lippincot Comp, 1974
Pharmaceutical Biotechnology, Daan J Crommelin, Fourth edition
Pharmaceutical Biotechnology, Daan J Crommelin, Fourth edition
Sambrook, J., Fritsch, E.F., Maniatis, T., Molecular Cloning: a Laboratory Manual, Cold Spring Harbor Lab. Press, 1989.
Sambrook, J., Fritsch, E.F., Maniatis, T., Molecular Cloning: a Laboratory Manual, Cold Spring Harbor Lab. Press, 1989.
Woodbury, C.P., Pharmaceutical Biotechnology: fundmentals and essentials, Interpharm Press, 1992.
Woodbury, C.P., Pharmaceutical Biotechnology: fundmentals and essentials, Interpharm Press, 1992.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 3
Work Hour outside Classroom (Preparation, strengthening) 14 7
Project (Including Preparation and presentation Time) 1 10
Report (Including Preparation and presentation Time) 1 10
Midterm Exam 1 1
Time to prepare for Midterm Exam 1 10
Final Exam 1 1
Time to prepare for Final Exam 1 10
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • ECTS credits and course workload