Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
ASYMMETRIC ORGANIC SYNTHESIS I 801300715750 3 + 0 3.0 8.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery Theoretical lectures and homeworks
Course Coordinator
Instructors
Assistants
Goals Understanding the basics of stereoselective synthetic methods after evaluation of stereochemical basic concepts together with importance and propertiesof stereoisomers
Course Content Introduction of asymmetric synthesis, history;Stereochemistry, basic terms;Stereoisomers, enantiomers, diasteromers their properties;Stereoselective synthesis;Chirelity induction and chirelity factors;Chiral pool;Bio-asymmetric synthesis
Learning Outcomes 1) Understanding the importance of stereochemistry
2) Discussing the factors effecting stereoselctivity
3) Using chirality factors in selectivity

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Introduction to asymmetric synthesis, importance and history Lecture

 Presentation (Including Preparation Time)
2. Week Stereochemistry: Stereochemical terms, nomenclature, terminology, enantiomers, diastereomers, general properties Lecture

 Presentation (Including Preparation Time)
3. Week Enantiomer and siastereomer properties, determination, chromatografic and spectroscopic methods Lecture

 Presentation (Including Preparation Time)
Double steroselective reactions Lecture

 Presentation (Including Preparation Time)
4. Week Purification of enantiomers and diastereomers, enrichment, resolution techniques Lecture

 Presentation (Including Preparation Time)
5. Week Principals of stereoselective and asymmetric synthesis, topology, overview Lecture

 Presentation (Including Preparation Time)
6. Week Chirelity factors, types and applications. Chiral catalysts Lecture

 Presentation (Including Preparation Time)
7. Week Chiral reagents, application, advantages and disadvantages Lecture

 Presentation (Including Preparation Time)
8. Week Chiral auxiliaries, types, application areas, advantages and disadvantages Lecture

 Presentation (Including Preparation Time)
9. Week Chiral pool: Natural chiral compounds (amino acids, carbohyrates etc.) utilisation in asymmetric synthesis as chiral source Lecture

 Presentation (Including Preparation Time)
10. Week Bioasymmetric synthesis Lecture

 Presentation (Including Preparation Time)
11. Week Enantiyoselective synthetic reaction examples Lecture

 Presentation (Including Preparation Time)
12. Week Diastereoselective reactions Lecture

 Presentation (Including Preparation Time)
13. Week Double steroslective rections Lecture

 Presentation (Including Preparation Time)
14. Week Kinetics and mechanism of stereoselective rections Lecture

 Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Organik bileşiklerin sterokimyası, Ernest Eliel, 1991.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 3
Work Hour outside Classroom (Preparation, strengthening) 5 10
Homework 2 10
Activity (Web Search, Library Work, Trip, Observation, Interview etc.) 2 10
Quiz 3 10
Time to prepare for Quiz 3 15
Midterm Exam 1 2
Time to prepare for Midterm Exam 1 10
Final Exam 1 2
Time to prepare for Final Exam 1 15
1 3
1 3
1 5
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • ECTS credits and course workload