Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
ASYMMETRIC ORGANIC SYNTHESIS II 801300715760 3 + 0 3.0 8.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery Theoretical lectures, homeworks and discussions
Course Coordinator
Instructors
Assistants
Goals Purpose of this course is evaluation of different asymmetric reaction types according to application of different chirality factors
Course Content Asymmetric synthesis reactions, classification;Asymmetric reduction reactions;Asymmetric oxidation reactions;Asymmetric C-C Bond formation;Asymmetric rearrangement reactions;Chiral enolates, isomerisation reactions;Asymmetric phase transfer reactions;Chiral organometallic reactives and their reactions
Learning Outcomes 1) Suggests asymmetric synthetic models depending on the type and mechanism of an organic reaction
2) Distingusih the difference in application of chirality factors in asymmetric synthesis
3) Understands the advantegous of chiral catalysts in asymmetric synthesis

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Classification of asymmetric synthesis reactions and general outlook Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
2. Week Asymmetric reduction reactions Lecture; Discussion

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3. Week Asymmetric hydrogenation reactions and reagents Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
4. Week Asymmetric heterogen catalysts Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
5. Week Asymmetric oxidation reactions Lecture; Discussion

Presentation (Including Preparation Time)
6. Week Asymmetric C-C bond formation Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
7. Week Asymmetric addition-elimination reactions Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
8. Week Asymmetric condensation reactions, aldol reactions Lecture; Question Answer

Presentation (Including Preparation Time)
9. Week Asymmetric rearrengments Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
10. Week Synthesis with chiral enolates Lecture; Discussion

Presentation (Including Preparation Time)
11. Week Asymmetric isomerisation reactions Lecture; Discussion

Presentation (Including Preparation Time)
12. Week Asymmetric phase transfer reactions Lecture; Question Answer

Presentation (Including Preparation Time)
13. Week Organometallic reactives in asymmetric synthesis Lecture; Question Answer; Discussion

Presentation (Including Preparation Time)
14. Week A general evaluation of asymmetric synthesis reactions Lecture; Question Answer; Problem Solving; Discussion

Presentation (Including Preparation Time)

Sources Used in This Course
Recommended Sources
Asimetrik organik tepkimeler, Morrison and Mosher
Asimetrik sentez, G.M. Coppola and H.F. Schuster, 1987
İleri Asimetrik Sentez, G.R. Stephenson.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 3
Work Hour outside Classroom (Preparation, strengthening) 6 10
Homework 5 5
Activity (Web Search, Library Work, Trip, Observation, Interview etc.) 6 5
Quiz 8 2
Time to prepare for Quiz 8 4
Midterm Exam 1 2
Time to prepare for Midterm Exam 1 10
Final Exam 1 2
Time to prepare for Final Exam 1 15
1 3
1 5
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information