Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
ADVANCED TOPICS IN PHARMACEUTICAL CHEMISTRY 34184069 0 + 0 3.0 3.0

Prerequisites None

Language of Instruction English
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors
Assistants
Goals It aims to give advanced knowledge about; examination of specific topics in medicinal chemistry, the concept of an ideal drug, chemical and physicochemical properties in terms of ideal drug design, pharmacokinetic properties, drug-receptor interaction of the various drugs in biological environment, stereochemistry and biological activity, metabolism, SAR-QSAR and parameters, certain structures in drug development and inspiration from them.
Course Content Ideal drug concept, Chemical and physicochemical properties of ideal drug in terms of drug design, Pharmacokinetic properties, Relationships of drug and receptors, Stereochemistry and biological effectiveness, Metabolism, Proteinkinase inhibitors, Topoisomerase inhibitors.
Learning Outcomes 1) Gives knowledge about nomenclature and synthesis information of heterocyclic compounds, peptids and organic compounds in various structures and industrial synthesis of pharmaceutical active agents in ideal drug development studies
2) Applies studies on design, synthesis, structure elucidation and analysis of pharmaceutically active substances.
3) Knowledge about new medicines and their properties.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week The concept of ideal drug Lecture; Question Answer
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
2. Week Chemical and physicochemical properties for ideal drug design Lecture; Question Answer
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
3. Week Pharmacokinetic properties Lecture; Question Answer
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
4. Week Drug-receptor relationships Lecture; Question Answer
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
5. Week Stereochemistry and biological activity Lecture; Question Answer
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
6. Week Metabolism Lecture; Question Answer; Discussion; Case Study
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
7. Week Protein kinase inhibitors Lecture; Question Answer
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
8. Week Protein kinase inhibitors Lecture; Question Answer
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
9. Week Protein kinase inhibitors Lecture; Question Answer
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
10. Week Topoisomerase inhibitors Lecture; Question Answer; Discussion; Case Study
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
11. Week Topoisomerase inhibitors Lecture; Question Answer
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
12. Week Telomerase inhibitors Lecture; Question Answer; Discussion; Case Study
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
13. Week Telomerase inhibitors Lecture; Question Answer; Discussion; Case Study
Colloquium
Problem Based Learning 		Presentation (Including Preparation Time)
14. Week Final exam


Sources Used in This Course
Recommended Sources
Methods and Principles in medicinal Chemistry in: QSAR: Hansch Analysis and Related Approaches volume 1, VCH Edited: R. Mannhold, P. Krogsgaard-Larsen, H. Timmerman 1993
The Practice of Medicinal Chemistry, Camille Georges Wermuth, Academic Press; 3 edition, 2008.

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY13000
PY23000
PY33000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 3
Work Hour outside Classroom (Preparation, strengthening) 14 1
Homework 14 1
Presentation (Including Preparation Time) 14 1
Final Exam 1 1
Time to prepare for Final Exam 8 1
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
Quick Access Hızlı Erişim Genişlet
Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload