Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
MOLECULAR BİOLOGY AND GENETİCS OF STEM CELLS 56981011 3 + 0 3.0 12.0

Prerequisites None

Language of Instruction English
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors
Assistants
Goals In this program it is aimed to tell genome organization, gene expression and regulation within the framework of stem cell.
Course Content The topics that will be told in the scope of cell molecular biology and genetics like genome organization, gene expression, translation, post-transcriptional and translational regulations, epigenetic modifications, cell cycle control, will also be evaluated within the framework of stem cell. In addition to stem cell molecular mechanisms in the organ generation and regeneration and cell aging, definition of cancer stem cells will also be included. Current topics as gene therapy and stem cell usage in gene therapy will also be discussed.
Learning Outcomes 1) Evaluates basic characteristics of stem cells
2) Defines molecular pathways of stem cells in the development period and in the organ and tissue generation.
3) Has the capacity of comparing stem cell genome organization, gene expression and control mechanisms with the normal cells'.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Molecular mechanisms in keeping basic characteristics of stem cells Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
2. Week Cellular and molecular mechanisms in stem cell differantation Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
3. Week Programming and molecular mechanisms in tissue/organ stem cells Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
4. Week Structure of chromatin, transcription Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
5. Week Post-transcriptional modifications Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
6. Week RNA and translation Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
7. Week miRNAs and their functions Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
8. Week Transcription and translation regulation Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
9. Week Epigenetic modifications Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
10. Week Cell cycle control Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
11. Week Molecular pathways of cancer stem cells Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
12. Week Molecular mechanisms of cell aging Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
13. Week Gene therapy and stem cells in gene therapy Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)
14. Week Exam Lecture; Question Answer; Problem Solving; Discussion; Case Study
Colloquium
 Activity (Web Search, Library Work, Trip, Observation, Interview etc.)

Sources Used in This Course
Recommended Sources
Alp Can. Kök Hücre. 2014
Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. The Cell. 2015
Phue Van Pham. Stem Cell Processing. 2016

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15555
PY25555
PY35555
PY45000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 8
Work Hour outside Classroom (Preparation, strengthening) 16 2
Presentation (Including Preparation Time) 2 2
Project (Including Preparation and presentation Time) 16 2
Activity (Web Search, Library Work, Trip, Observation, Interview etc.) 16 2
Practice (Teaching Practice, Music/Musical Instrument Practice , Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice) 16 2
Time to prepare for Midterm Exam 8 2
Final Exam 2 2
Time to prepare for Final Exam 16 2
16 2
16 2
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload