Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
STEM CELL MOLECULAR BIOLOGY AND GENETICS 56981015 2 + 2 3.0 8.0

Prerequisites None

Language of Instruction English
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors Ceylan Verda BİTİRİM
Assistants
Goals In this program it is aimed to tell genome organization, gene expression and regulation within the framework of stem cell.
Course Content The topics that will be told in the scope of cell molecular biology and genetics like genome organization, gene expression, translation, post-transcriptional and translational regulations, epigenetic modifications, cell cycle control, will also be evaluated within the framework of stem cell. In addition to stem cell molecular mechanisms in the organ generation and regeneration and cell aging, definition of cancer stem cells will also be included. Current topics as gene therapy and stem cell usage in gene therapy will also be discussed.
Learning Outcomes 1) Evaluates basic characteristics of stem cells
2) Defines molecular pathways of stem cells in the development period and in the organ and tissue generation.
3) Has the capacity of comparing stem cell genome organization, gene expression and control mechanisms with the normal cells'.

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Molecular mechanisms in keeping basic characteristics of stem cells Lecture

Homework
2. Week Cellular and molecular mechanisms in stem cell differantation Lecture

Homework
3. Week Programming and molecular mechanisms in tissue/organ stem cells Lecture

Homework
4. Week Kromatin yapısı, transkripsiyon Lecture

Homework
5. Week Post-transkripsiyonel düzenlemeler Lecture

Homework
6. Week RNA ve translasyon Lecture

Homework
7. Week miRNAlar ve rolleri Lecture

Homework
8. Week Transkripsiyon ve translasyon regülasyonu Lecture

Homework
9. Week Epigenetik modifikasyonlar Lecture

Homework
10. Week Cell cycle control Lecture

Homework
11. Week Molecular pathways of cancer stem cells Lecture

Homework
12. Week Molecular mechanisms of cell aging Lecture

Homework
13. Week Gene therapy and stem cells in gene therapy Lecture

Homework
14. Week Exam Lecture

Homework

Sources Used in This Course
Recommended Sources
Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. The Cell. 2015

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15000
PY25000
PY35000
PY45000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 8
Work Hour outside Classroom (Preparation, strengthening) 8 2
Presentation (Including Preparation Time) 4 1
Project (Including Preparation and presentation Time) 8 2
Practice (Teaching Practice, Music/Musical Instrument Practice , Statistics, Laboratory, Field Work, Clinic and Polyclinic Practice) 16 2
Final Exam 1 2
Time to prepare for Final Exam 8 2
4 5
16 1
2 3
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
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Course Information