Course Information


Course Information
Course Title Code Semester L+U Hour Credits ECTS
THE MOLECULAR AND CELLULAR BASIS OF CARDIOVASCULAR SYSTEM DYSFUNCTION IN METABOLIC DYSORDERS 57402045 2 + 0 2.0 4.0

Prerequisites None

Language of Instruction Turkish
Course Level Graduate Degree
Course Type Compulsory
Mode of delivery
Course Coordinator
Instructors
Assistants
Goals To investigate the cellular and molecular basis of association between cardiovascular dysfunction and metabolic disorders by using biophysical techniques and interpretations.
Course Content The general properties of metabolic disorders in mammalians, the physiologica-biophysical processes in heart-vessel systems associated with metabolic disorders, the effect of metabolic disorders (hyperglycemia and hyperinsulinemia) on electrical activity of cardiomyocytes, The relation between ATP and function of cells, relationship between ATP and oxidative stress in cells.
Learning Outcomes 1) To have theoretical and pratical knowledge about relation between metabolism and nutriştion in mammalians
2) To understand the importance of nutritional-metabolic energy on electrical excitabile cells
3) To have knowledge about energy and function in heart and vessels

Weekly Topics (Content)
Week Topics Teaching and Learning Methods and Techniques Study Materials
1. Week Basic physiological-biophysical processes in metabolism of heart-vessel tissue Lecture; Question Answer; Problem Solving
Brainstorming
Brain Based Learning 		Homework Presentation (Including Preparation Time)
2. Week Effect of metabolic disorders on heart-vessel functions Lecture; Question Answer
Brainstorming; Large Group Discussion
Brain Based Learning 		Homework Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
3. Week Effect of metabolic disorders on electrical properties of cardiomyocytes Lecture; Question Answer
Brainstorming; Large Group Discussion
Brain Based Learning 		Homework Presentation (Including Preparation Time)
4. Week The relation between ATP and properties of cells Lecture; Question Answer
Brainstorming; Large Group Discussion
Brain Based Learning 		Homework Presentation (Including Preparation Time)
5. Week Hücrelerde ATP seviyesi ve oksidatif stres ilişkisi Lecture; Question Answer; Problem Solving; Discussion
Brainstorming; Large Group Discussion
Brain Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time) Report (Including Preparation and presentation Time)
6. Week Molecular mechanisms of the effect of metabolic disorders on properties of cells Lecture; Question Answer; Problem Solving
Brainstorming; Large Group Discussion
Brain Based Learning 		Homework Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
7. Week The physiological-biophysical processes in the electrical activities of cells Lecture; Question Answer
Brainstorming; Large Group Discussion
Brain Based Learning 		Homework Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
8. Week Metabolic pathways in the excitation-contraction of cells Lecture; Question Answer; Problem Solving
Brainstorming; Large Group Discussion
Problem Based Learning 		Homework Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
9. Week Effect of oxidative stress on the electrical properties of cells Lecture; Question Answer
Brainstorming; Large Group Discussion
Scenario Based Learning 		Homework Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
10. Week Effects of nutrition an tissue and cell functions Lecture; Question Answer; Problem Solving
Brainstorming; Large Group Discussion
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
11. Week Physical basis of the effect of metabolic disorders on the function of cells Lecture; Question Answer; Problem Solving
Brainstorming; Large Group Discussion
Scenario Based Learning; Brain Based Learning 		Homework Presentation (Including Preparation Time) Project (Including Preparation and presentation Time)
12. Week Molecular basis of the effect of metabolic disorders on the function of cells Lecture; Question Answer; Problem Solving
Brainstorming; Large Group Discussion
Brain Based Learning 		Homework Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
13. Week Overview of general subjects Problem Solving; Discussion
Brainstorming; Large Group Discussion
Brain Based Learning 		Presentation (Including Preparation Time) Report (Including Preparation and presentation Time)
14. Week final exam Question Answer
Brainstorming
Brain Based Learning 		Activity (Web Search, Library Work, Trip, Observation, Interview etc.)

Sources Used in This Course
Recommended Sources
Ackerman E., Ellis L.B.M., Williams L.E., Biophysical Science, 2. Baskı, Prentice-Hall Inc., 1979
Goldman's Cecil Medicine, Ed. Lee Goldman and Andrew I. Schafer (2016) 25 Edition. Elsevier Saunders Publishing ISBN-13: 978-1455750177 ISBN-10: 1455750174
Harpers Illustrated Biochemistry. Robert K. Murray, Peter J. Kennelly, David A. Bender, Kethleen M. Botham, P. Anthony Weil, Victor W. Rodwell (2015) 30th Edition (A & L Lange Series) ISBN: 9780071792776
Patton H.D., Fuchs A.F., Hille B., Scher A.M., Steiner R., Texbook of Medical Physiology, 1989

Relations with Education Attainment Program Course Competencies
Program RequirementsContribution LevelDK1DK2DK3
PY15554
PY25000
PY35000
PY45000

*DK = Course's Contrubution.
0 1 2 3 4 5
Level of contribution None Very Low Low Fair High Very High
.

ECTS credits and course workload
Event Quantity Duration (Hour) Total Workload (Hour)
Course Duration (Total weeks*Hours per week) 14 2
Work Hour outside Classroom (Preparation, strengthening) 14 2
Homework 2 12
Midterm Exam 1 1
Time to prepare for Midterm Exam 1 14
Time to prepare for Final Exam 14 2
Total Workload
Total Workload / 30 (s)
ECTS Credit of the Course
Quick Access Hızlı Erişim Genişlet
Course Information
  • Course Information
  • Weekly Topics (Content)
  • Sources Used in This Course
  • Relations with Education Attainment Program Course Competencies
  • ECTS credits and course workload